Search on: NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 1 
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Descriptor English:   Nuclear Receptor Subfamily 1, Group F, Member 1 
Descriptor Spanish:   Miembro 1 del Grupo F de la Subfamilia 1 de Receptores Nucleares 
Descriptor Portuguese:   Membro 1 do Grupo F da Subfamília 1 de Receptores Nucleares 
Tree Number:   D12.776.189.437
D12.776.260.698.209.100
D12.776.826.209.100
D12.776.930.669.209.100
Definition English:   A DNA-binding orphan nuclear receptor that positively regulates expression of ARNTL TRANSCRIPTION FACTORS and is a regulatory component of the circadian clock system. The protein also has a role in neuron cell survival and differentiation in that loss of function mutations of its gene result in the mouse phenotype referred to as the STAGGERER MOUSE. 
History Note English:   2010(1996) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   53641 
Unique Identifier:   D057094 

Occurrence in VHL:
 

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